The image features a sleek, black horse in mid-stride against a black background, emphasizing its muscular build and graceful movement. The text "PSSM1" and "Polysaccharide Storage Myopathy Type 1" is displayed prominently in pink at the top left corner. At the bottom, a pink banner with the text "PSSM1 Clear" indicates a negative result for the PSSM1 genetic test.

PSSM1 Polysaccharide Storage Myopathy Type 1

Verkoper: Equigerminal
Normale prijs: €43.05
Aanbiedingsprijs: €43.05
Eenheidsprijs: per

Inclusief belasting Verzendkosten worden berekend bij het afrekenen.

Turnaround time

Aantal

Hoeveelheid moet 1 of meer zijn

About the Test

The PSSM1 DNA test verifies the presence of the affected allele at the GYS1 locus responsible for Polysaccharide Storage Myopathy Type 1 (PSSM1).

Sample Collection

Hair Roots: 20 to 30 hair roots. Pull the hair and tape it onto the printable sample submission form.
Blood Sample: 5 mL blood in a K3 EDTA tube. Collect the blood and send the tube together with the printable sample submission form.

Turnaround Time

Standard Processing: Results in 5 working days after sample arrival at the laboratory. Clients organize and cover the costs of sending the samples.
Premium Processing: Results in 1-2 days after sample arrival. Includes free express delivery. For an additional fee of €35, the laboratory organizes express shipping with pick-up from the client's address (available for non-remote regions).

Why Test?

This genetic test helps breeders identify horses carrying the PSSM allele. Informed breeding choices can prevent the birth of affected foals. While PSSM cannot be cured, muscle function can be managed with dietary changes and exercise routines.

The PSSM1 test is required by many studbooks and is highly recommended when considering the purchase of a horse. Testing for PSSM1 as part of the pre-purchase examination can ensure that you are making an informed decision, as the condition can impact the horse's performance and overall health.

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Results Description

The DNA test results will be one of the following:

n/n: Negative for PSSM1. No affected allele present.
n/P1: Positive heterozygous for PSSM1. One mutated allele present. The horse can pass the PSSM1 allele to 50% of its progeny.
P1/P1: Positive homozygous for PSSM1. Two mutated alleles present. The horse will pass the PSSM1 allele to 100% of its offspring.

Additional Information

Polysaccharide Storage Myopathy (PSSM1) is a hereditary muscle disease that affects many breeds. The condition is caused by a mutation in the GYS1 gene, leading to an abnormal accumulation of glycogen in the muscles. This can cause symptoms such as muscle tremors, stiffness, reluctance to move, and excessive sweating. Management of PSSM1 includes dietary changes and regular exercise to help mitigate symptoms.

Check our FAQs for more information

FAQs

What breeds are affected by PSSM1?

PSSM1 affects many breeds, including Quarter Horses, Belgian Draft Horses, and Warmbloods. The prevalence of the mutation varies by breed, with some breeds having a higher incidence of the condition.

How is PSSM1 inherited?

PSSM1 is inherited in an autosomal dominant manner, meaning that horses with one (n/P1) or two (P1/P1) copies of the mutated gene can develop the disease. Horses with two copies generally show more severe symptoms.

How can PSSM1 be managed?

Management includes dietary modifications to reduce starch and sugar intake, and a consistent exercise regimen. These measures can help prevent the onset of symptoms or reduce their severity.

Visit our full FAQ page for more details.